New real sun-tan drug may help prevent cancer

New real sun-tan drug may help prevent cancer

While describing the finding thoroughly, Professor David Fisher, the lead researcher from Massachusetts General Hospital said: "Under the microscope, it's the real melanin, it really is activating the production of pigment in a UV-independent fashion".

The drug, when applied to the skin in the form of gentle rubbing, works in the format of a wide chain of chemical reactions and ultimately creates a layer of the pigment melanin. "It would just be sunless".

"Human skin is a very good barrier and is a formidable penetration challenge".

That was a pretty big deal, because when your red-headed friend complains about going from pale to a straight-up burn when they hit the beach - with no tan in between - they're not just overreacting.

A method that gives mice a tan without using ultraviolet radiation now works in human skin samples.

"We are excited about the possibility of inducing dark pigment production in human skin without a need for either systemic exposure to a drug or UV exposure to the skin", said Fisher.

For years, Fisher and his team have been studying how UV radiation triggers the production of melanin.

"We believe the potential importance of this work is towards a novel strategy for skin cancer prevention", Fisher says.

But there was one problem. If the compound proves safe for human use, it would provide tanners an alternative to the illicitly used synthetic hormone called melanotan, which has been associated with skin cancer.

Now, a decade later, the researchers have come up with a solution that they think will actually work on us - a different class of compounds that cannot only boost the pigmentation process, but also squeeze through the outer layers of our epidermis. Their study, reported in the June 13 issue of Cell Reports, is a follow-up to a 2006 study that identified the molecular pathways underlying the tanning response and induced tanning in a strain of mouse that normally does not produce the protective, dark form of melanin.

Red-furred mice in the study turned nearly black with a big enough dose of the drug, International Business Times reported. This artificial tan lasted several days. On the left, it has been treated with a control or the substance less able to penetrate human skin and shows no change.

Scientists have come up with a drug that could help people tan without exposure to the sun.

But if it lives up to its promise, this compound would do more than just bankrupt the fake tan industry - when used in conjunction with sunscreen, it could help cut the rate of skin cancer, which is now the most common cancer in the United States, affecting one in five Americans over their lifetime. Melanin is known to provide some UV protection, although the team didn't test this on the redhead mice in this study. "We could see that the skin starts to turn dark".

Related Articles

  • Attorney General Jeff Sessions says he was never briefed on Russia probe

    Attorney General Jeff Sessions says he was never briefed on Russia probe

    He recused himself from the Russia investigation after the meetings with the Russian ambassador were publicized in the news media. Angus King, I-Maine, Sessions declined to say whether he believes Russian Federation attempted interfere in last year's election.

    US college student released by North Korea home, but in coma

    Tillerson announced that the Department of State had secured Warmbier's release at the direction of the Republican president. A White House official says the May meeting in Oslo was attended by Joseph Yun, the US envoy to North Korea .

    Attorney General Jeff Sessions denies 'false and scurrilous allegations'

    Sessions said that he was not sure what was "explicitly" in Trump's mind when he made a decision to fire Comey. As Trump tried to shoo everyone out to talk alone with Comey, Sessions lingered, in Comey's account.
  • Kent State freshman football player dies after conditioning workout

    Tyler was transported to a local hospital by paramedics this morning following football conditioning drills at Dix Stadium. He was taken to University Hospitals Portage Medical Center where doctors reportedly worked on him for two hours.

    Warriors Win 2017 NBA Championship

    The Warriors tallied 35 bench points in game five, while Cleveland managed just seven points outside their starting five. After getting outscored 37-33 in the first quarter , Golden State responded by taking an 11-point lead into the break.
    Champion Golden State Warriors To Opt Out Of White House Visit

    Champion Golden State Warriors To Opt Out Of White House Visit

    Their best chance was to roll the dice and pray a major piece in Cleveland or Golden State got hurt and gave them an opportunity. Cleveland got off to a fast start and built a 41-33 lead on a dunk by James early in the second quarter.
  • May apologises to own MPs for election 'mess'

    As a Catholic, I should be flattered by the liberals' righteous fury: the Protestant DUP are the stuff of sectarian nightmares. May is due to begin Brexit negotiations with Brussels on June 19 in a weaker position than before the June election.

    Trump to tout apprenticeships as way to fill jobs gap

    That means the presidency and the public will be subjected to even more of what we've seen so far - and it might just get worse. The president toured a classroom full of tool-and-die machines that simulated a factory floor, accompanied by Wisconsin Gov.

    Dodgers' Puig makes obscene gesture at Cleveland fans

    After hitting the home run to right-center field, Puig appears to flip double middle fingers to someone in the crowd in Cleveland. That was definitely the case on Tuesday night when the Los Angeles Dodgers faced off with the Cleveland Indians.
  • Democrats Fuming Over Sessions' Refusal to Answer Questions

    Sessions recused himself from the Russian Federation investigation in March after the revelations of the two Kislyak meetings. In March he acknowledged he met twice a year ago with Russia's ambassador to Washington, Sergei Kislyak.

    Tom Holland Accidentally Reveals 'Spider-Man' Will Be a Trilogy

    Tom Holland just revealed that there's more Spider-Man movies to come! Yet another Marvel movie, "Spider-Man: Homecoming " releasing on 28th June will also divulge the new Audi A8 L.

    Xbox One X: Microsoft's Gaming Comeback or Just Another PS4 Pro?

    Sony is comfortably in the lead in the video game market and can just continue to dominate with exciting PS4 games. The most powerful game console will cost $600 in Canada on November 7 when the Xbox One X is released worldwide.